This excellent book is a concise yet thorough examination of the important and emerging field of the study of biological risk factors in drug abuse. Historically, drug abuse research has concentrated on the contributions of environmental and behavioral factors as the major influences on addiction. The revelatory studies in this volume examine the genetic contributions to drug taking behavior through the use of animal models, cellular experiments and human clinical studies. Behavioral and Biochemical Issues in Substance Abuse provides for the first time in one volume, up-to-date, easily digested reviews of topics concerning biological and genetic factors in drug abuse. Medical researchers in all areas of alcoholism and drug abuse, researchers in pharmacology, psychology, psychiatry and neuroscience, and clinicians interested in biological approaches to alcoholism and drug abuse problems will benefit greatly from this valuable resource. Authoritative contributors clearly demonstrate the capability of genetic factors to modulate the reinforcing or rewarding effects of drugs, thereby altering their addictive potential. In addition to gaining comprehension of the biological factors affecting addiction, a greater understanding of genetics related to drug abuse will enable future research to control biological factors, leading to more accurate studies of behavioral and environmental influences on drug and alcohol abuse.

Oxford successful tourism is a trusted Tourism course that is used by teachers all over South Africa. The rich, relevant, and age appropriate content fully covers the National Curriculum and Assessment Policy Statement (CAPS) and is enriched by the most recent tourism statistics, ensuring that learners stay interested throughout the year. Features: topics are structured according to CAPS which makes the course easy to use in the classroom; the scaffolded content and concepts are comprehensively illustrated with logos and industry examples to provide with a solid foundation for exam success; a full-colour mapwork section covers all that learners need to know, and more, in Grade 10; appropriate language levels make content accessible, build learner confidence and support independent learning and revision; activities and questions for revision and extension are based on exam type questions, ensuring learners are thoroughly prepared for exams; exam support is built into every activity, revision, practice test and practice exam.

This excellent book is a concise yet thorough examination of the important and emerging field of the study of biological risk factors in drug abuse. Historically, drug abuse research has concentrated on the contributions of environmental and behavioral factors as the major influences on addiction. The revelatory studies in this volume examine the genetic contributions to drug taking behavior through the use of animal models, cellular experiments and human clinical studies. Behavioral and Biochemical Issues in Substance Abuse provides for the first time in one volume, up-to-date, easily digested reviews of topics concerning biological and genetic factors in drug abuse. Medical researchers in all areas of alcoholism and drug abuse, researchers in pharmacology, psychology, psychiatry and neuroscience, and clinicians interested in biological approaches to alcoholism and drug abuse problems will benefit greatly from this valuable resource. Authoritative contributors clearly demonstrate the capability of genetic factors to modulate the reinforcing or rewarding effects of drugs, thereby altering their addictive potential. In addition to gaining comprehension of the biological factors affecting addiction, a greater understanding of genetics related to drug abuse will enable future research to control biological factors, leading to more accurate studies of behavioral and environmental influences on drug and alcohol abuse.

Have the social safety nets, environmental protections, and policies to redress wealth and income inequality enacted after World War II contributed to declining rates of dementia today-and how do we improve brain health in the future? Winner of the American Book Fest Health: Aging/50+ by the American Book Fest, Living Now Book Award: Mature Living/Aging by the Living Now Book Awards For decades, researchers have chased a pharmaceutical cure for memory loss. But despite the fact that no disease-modifying biotech treatments have emerged, new research suggests that dementia rates have actually declined in the United States and Western Europe over the last decade. Why is this happening? And what does it mean for brain health in the future? In American Dementia, Daniel R. George, PhD, MSc, and Peter J. Whitehouse, MD, PhD, argue that the current decline of dementia may be strongly linked to mid-twentieth century policies that reduced inequality, provided widespread access to education and healthcare, and brought about cleaner air, soil, and water. They also * explain why Alzheimer's disease, an obscure clinical label until the 1970s, is the hallmark illness of our current hyper-capitalist era; * reveal how the soaring inequalities of the twenty-first century-which are sowing poverty, barriers to healthcare and education, loneliness, lack of sleep, stressful life events, environmental exposures, and climate change-are reversing the gains of the twentieth century and damaging our brains; * tackle the ageist tendencies in our culture, which disadvantage both vulnerable youth and elders; * make an evidence-based argument that policies like single-payer healthcare, a living wage, and universal access to free higher education and technical training programs will build collective resilience to dementia; * promote strategies that show how local communities can rise above the disconnection and loneliness that define our present moment and come together to care for our struggling neighbors. Ultimately, American Dementia asserts that actively remembering lessons from the twentieth century which help us become a healthier, wiser, and more compassionate society represents our most powerful intervention for preventing Alzheimer's and protecting human dignity. Exposing the inconvenient truths that confound market-based approaches to memory enhancement as well as broader social organization, the book imagines how we can act as citizens to protect our brains, build the cognitive resilience of younger generations, and rise to the moral challenge of caring for the cognitively frail.